Histopathology of gastrointestinal neuroendocrine neoplasms

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Histopathology of gastrointestinal neuroendocrine neoplasms

Gastrointestinal neuroendocrine neoplasms (GI-NENs) arise from neuroendocrine cells distributed mainly in the mucosa and submucosa of the gastrointestinal tract. In 2010, the World Health Organization (WHO) classification of NENs of the digestive system was changed, categorizing these tumors as grade 1 neuroendocrine tumor (NET), grade-2NET, neuroendocrine carcinoma (large- or small-cell type),...

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Diagnosis and therapy of neuroendocrine neoplasms of the gastrointestinal tract

A neuroendocrine neoplasm (nen) is a tumor that originates in neuroendocrine cells capable of producing peptides or amines. neuroendocrine neoplasms of the digestive system are also referred to as gastroenteropancreatic neuroendocrine neoplasms (GeP nen) and constitute a heterogeneous group of growths originating from at least 15 types of specialized cells spread throughout the stomach, small i...

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ژورنال

عنوان ژورنال: Frontiers in Oncology

سال: 2013

ISSN: 2234-943X

DOI: 10.3389/fonc.2013.00002